Talent has become the most important resource for organizations across a wide range of sectors throughout the world including business, non-profit, and government. These organizations are now engaged in an increasingly fierce competition to acquire the best talent as they seek to gain the upper hand in today’s fast changing environment. By combining the body of knowledge on entrepreneurship and talent management from a global perspective, this book provides a synthesized understanding of entrepreneurial mobility and talent management in the entrepreneurship and innovation ecosystem. The expert contributors combine empirical evidence and case studies to provide a nuanced understanding of global talent management from an international comparative perspective. The topics discussed include China’s return migration and its impact on Chinese development, local engagement and transformation of Chinese communities in England, and reverse migration from the US to China. Furthermore, from a comparative perspective, contributors examine global talent and entrepreneurial mobility in the contexts of Silicon Valley, European university spin-off practices, entrepreneurial ecosystem in France, Italy, and South Korea, respectively. Scholars and students in entrepreneurship and talent management will find the scope for future research useful in their work. Entrepreneurs, managers, and policymakers will benefit from the examination of global perspectives and different national contexts.